Tuesday, January 19, 2010

What are life-threatening disease, a genetic tendency to

Why do some people lavish meals a day is not sight of blood pressure is increased, some people with diabetes have to gently? Why some people are not suffering from a lifetime of smoking lung disease, some signs of human habitation is not long but very early age of lung cancer? It is clear This is because each person different diseases, genetic predisposition. Some people susceptible to the disease, some people also susceptible to the kind of disease.

So, you kind of disease susceptibility? Kinds of diseases that have obvious genetic inclination? This issue's special planning, let us under the guidance of experts and learn to draw the "family disease spectrum", depending on the disease genealogy tips, to develop personalized family health care plan.

The disease can also be born with

A family of "cancer curse"

Bradfield family, this is an ordinary American family, but since the family's old grandmother戈尔布拉德Rumsfeld, died of stomach cancer in 1960, after the shadow of death has been shrouded her children and grandchildren.

It turned out that Al Gore since the old lady died of gastric cancer, a descendant of the family members have died over the same diseases. Gore has seven children, six of them in their forty to fifty years of age have died of cancer. In the Bradfield family of 18 grandchildren (female) and grandson (female), the David Allen died in 2003 a family of genetic disease. Her family is like being a "curse of gastric cancer", a total of 10 persons were suspected gastric cancer or gastric cancer has died.

Shortly thereafter, the family of the remaining 17 people have received genetic testing results show that there were 11 of them carry a hereditary gene mutations in gastric cancer. According to scientific research personnel, carrying the mutant gene, offspring will have a 70% chance of suffering from stomach cancer. No alternative but to Bradfield family of 11 brothers and sisters have chosen their places in their time of onset will not stomach completely removed.

In fact, the phenomenon of familial aggregation of cancer not only in the abroad, at home, this sort of thing is also not uncommon. For example some time ago the media had reported: Nanchang Schomburgk Three of four brothers decided to work in Guangzhou and the second oldest bears the water leaving the root. Last year, in June, bears the root of illness to the hospital for examination of water, the result is colorectal. The three brothers back overnight. That second child's condition, three heart Yi Zheng, such symptoms themselves have a wow. Check the results were shocking, with the exception youngest just some inflammation, the eldest, fourth eldest among them had colorectal.

Coincidentally, Harbin, Ms. King was found suffering from lymphoma, neck, and her sister, found himself in the care process also appears to have a mass, after examined, and she also got the disease; later, as far away as South Korea Simei and niece went so far as also identified a malignant lymphoma. Hong Kong singer Anita Mui, in her factor of cervical cancer before his death in 2004, her sister had been in 2000 for the same disease died.

Concerned about the disease, genetic predisposition

These "cancer family" of course, some "extreme" example of many diseases is a genetic "tendency", and will not be 100% to the genetic. But whether seen or heard from day to day or from the scientific point of view, said many families with a hereditary disease, it is an indisputable fact.

In other words, before the disease, not everyone is equal. Each person's susceptibility to different diseases, as well as unhealthy lifestyle, tolerance is not the same. Like every person born there is the difference between height, fat, thin, each with different diseases, "affinity" not the same. For example, some people I never smoke eventually got lung cancer, while others had a lifetime of cigarette smoking did not eventually get lung cancer, which makes some smokers to "luck" that smoking itself may also be all right. In fact, this is a family of genetic susceptibility to at work. In fact, those families better genetic background population, certainly in the long term after smoking some cells of the mutation, but his body repair genes can be repaired quickly to avoid such damage to cancerous cells; while some poor immune function susceptible population is likely due to lung cancer and smoking is harmful stimulation.

Recognizing this point, we can trace the prevalence of other members of the family learned that their susceptibility to disease, which enable it to undertake targeted prevention. For example, if your family has several family members suffering from diabetes, then you should the risk of diabetes is much greater than the average person, we should pay particular attention to monitoring and prevention of diabetes.
Six major diseases and genetic correlation

Many diseases have a clear genetic predispositionSome are born suffering from certain diseases than other people taking big chances. So, what common disease has a genetic tendency? If they are at high risk of these diseases, but also how to plan ahead, blocking it themselves renew?

1. Hypertension

Genetic risk: ★ ★ ★ ★ ★

Scientists have bred a kind of "genetic spontaneous hypertension," mice. This mouse gene with hypertension will pass from generation to generation, their children and grandchildren will happen 100% of high blood pressure, which is closely related to high blood pressure and genetic most typical example.

At present, most scholars believe that high blood pressure are more genetic disease. Hypertensive patients by family survey found that parents were suffering from high blood pressure, their children's future probability of suffering from high blood pressure as high as 45%; a parent suffering from hypertension for the sick, the children likely to suffer from high blood pressure is 28%; while their parents with normal blood pressure the probability of children suffering from high blood pressure was only 3%.

Prevention Principles

1. Insist on monitoring of blood pressure, a normal state for at least 1 per year.

2. Potassium salt restriction. Gradually the amount of control over the daily salt intake to 5 grams, and eat more potassium-rich fruits, vegetables (such as banana, walnut, lotus seeds, coriander, amaranth, spinach, etc.).

3. To prevent overweight and obesity.

4. Quitting alcohol limit.

2. Diabetes

Genetic risk: ★ ★ ★ ★ ★

Diabetes has a significant genetic predisposition (especially the most common clinical type 2 diabetes). Family study found that positive family history of diabetes, the crowd, their diabetes was significantly higher than family history-negative groups. Whose parents have diabetes, their children's chances of suffering from diabetes, 15 to 20 times that of ordinary people.

Prevention Principles

-Induced diabetes, "external" There are too many calorie intake, decreased activity, obesity, smoking and psychological stress too much so. In turn, these factors can prevent diabetes prevention. In the diet, it should be food, Roudan Nai, vegetables, fruits, a reasonable match, pay attention to balance between intake and consumption. Often measured body weight, if weight gain, and caloric intake certainly excessive, then it should review your diet and increase exercise.

3. Dyslipidemia

Genetic risk: ★ ★ ★

There are many reasons for abnormal lipid metabolism, one of which is that genetic factors. With the development of medical science has now been found that a considerable part of the lipid abnormalities in patients with one or more genetic defects. Dyslipidemia caused by genetic defects with familial aggregation of more than there is an obvious genetic predisposition, clinically known as familial dyslipidemia.

Prevention Principles

The most important is the emphasis on "stride leg, pipe shut up." On the one hand to appropriately limit the diet, but the types of food should be abundant, choose low-fat food (vegetable oil, yogurt), an increase of vitamins, fiber (fruits, vegetables, bread and cereal food), weight control. While strengthening exercise, calories consumed so that it does not cause accumulation of fat in the body

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