Female life, the number of follicles in the fetal period reserve a foregone conclusion, no increase after birth. Baby girl born about 200 follicles within the ovary million, 30 million adolescent about -40 million left, under normal circumstances, the monthly discharge of a mature follicle, women excreted about 400 life mature follicles, and the remaining 99.9% of the follicles are at different stages of degradation in the developing apoptosis. When the follicle depletion, which entered the menopause. There is no way to accurately measure the number of follicles. However, ultrasound can be used in indirect measurement of ovarian follicle size and number.
The more difficult the older pregnant women is a common sense, but in the past for the rate of follicle loss has not depth. January 2010, in the "WHAS11" published an article by Ed Andrews in Scotland and Edinburgh University to complete the relevant papers, the object of this study is from the UK, U.S. and European 325 women of different ages, the results show that with increasing age, women lose the speed of the egg faster than we imagine, women 30 years old has lost 90% of the follicles, almost all of the quality of ovarian follicles has been discharged, to 40 years old, only under 3% of the follicles. This fertility decline is irreversible, and it is not prevented, but by smoking cessation, weight loss, and reducing stress can slow down the rate of loss of fertility. Long-term use of contraceptives does not affect women's fertility or the number of follicles.
With increasing age, lower quality follicles, increasing the difficulties of pregnancy and the risk of fetal malformations, which all assisted reproductive technology is a challenge. Therefore, to female friends once again reminder: If you plan to have children, it should be the sooner the better, if you delay too long may result in permanent fertility problems to conceive. 40 healthy women over the age of their fertility can not be blind to the self-confidence, even if the use of advanced assisted reproductive technologies, in this age group a success rate of only about 10%.
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